• Rajat Singh

    Graduate Student

I received undergraduate degrees in Biochemistry and Neuroscience from the University of Delhi (New Delhi, India) and Washington State University (Pullman, WA) in 2006 and 2008 respectively. In November 2008, after receiving the NCI Cancer Research Training Award, I started working in the lab of Dr. Robert Kreitman (Clinical Immunotherapy Section, Lab of Molecular Biology, CCR, NCI, Bethesda, MD). At the NCI, I was involved in a pre-clinical assessment of combination therapies of the anti-CD25 immunotoxin, LMB-2, with chemotherapeutic agents.

In 2010, I received the Intramural Research Training Award from the NINDS and started working in the lab of Dr. Craig Blackstone (Cellular Neurology Section, NINDS, Bethesda, MD) where I worked on projects focusing on the pathological mechanisms contributing to hereditary spastic paraplegias-SPG11, SPG15 and SPG20.

I joined the Immunology and Microbial Pathogenesis program at Weill Cornell Graduate School of Medical Sciences in August 2012 and a year later started my thesis project in the Melnick Lab. My research focuses on the role of a putative Locus Control Region (located upstream of BCL6) as a platform for epigenetic regulation of the germinal center reaction. I am also studying the role of specific long non-coding RNAs that are differentially expressed during B-cell development and the mechanisms that may contribute to the fine-tuning of transcriptional regulation during the germinal center stage.