• Maria Del Pilar Dominguez Rodriguez

    Post-Doctoral Fellow

I received my PhD in Molecular Biology from the Universidad Autonoma de Madrid (Spain). During my PhD I focused on models of bacterial infection and inflammatory conditions and developed as a scientist with an expertise in Immunology, especially in the biology of dendritic cells. In 2013 I joined Dr. Rita Shaknovich lab at WCMC to study the epigenetic evolution of diffuse large B cell lymphomas (DLBCLs), a group of aggressive B-cell tumors that arise from germinal center B cells. I used mouse models to analyze the role of activation-induced deaminase (AID) in the DNA methylation landscape of germinal center B cells. Following my goal to develop new therapeutic approaches and find novel biomarkers for B-cell lymphomas, I joined the group of Dr. Ari Melnick at WCMC in 2015 to continue working in the DNA methylation mechanisms that are deregulated specifically during the formation of germinal center-derived lymphomas.