• Ling Wang

    Research Technician

Using lentivirus system to mediate gain and loss of function in cancer cells: Generating recombinant DNA plasmids, producing them in mammalian cells to make virus, determining their impact on RNA expression, and test them in human cancer cells; FACS; Virus titration.

Metabolomic profiling of tumors and drug responses: Metabolite levels can be regarded as the amplified output of biological systems in response to several stimuli (genetic, epigenetic, environmental, etc). In the past years technologies have been developed that allow comprehensive and quantitative investigation of a multitude of different metabolites, which is called "metabolomics". We use metabolomic techniques to understand the metabolic status of tumors under several conditions and to develop therapeutic strategies based on metabolic signatures.